Cefuroxime Axetil
- Product Name : Cefuroxime Axetil
- Product Code: ATM033CEF
- Grade : BP / EP / USP
- Therapeutic Category : Antibiotic
- CAS No : 64544-07-6
- COA : Available
- MSDS : Available
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Description
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Specification:
Description
Cefuroxime is an enteral second-generation cephalosporin antibiotic.
As with the other cephalosporins, it is susceptible to beta-lactamase, although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike most other second-generation cephalosporins, cefuroxime can cross the blood-brain barrier.
Specification:
| Chemical Name | Cefuroxime Axetil |
| Synonyms | (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Altacef; Bioracef; CCI 15641; Cefaks; Cefazine; Ceftin; Cefurax; Cefuroxime 1-Acetoxyethyl Ester; Elobact; Forcef; Oraxim; Zinat; Zinnat; |
| CAS Number | 64544-07-6 |
| Molecular Formula | C₂₀H₂₂N₄O₁₀S |
| Appearance | White to Pale Yellow Solid |
| Melting Point | 108 – 120°C |
| Molecular Weight | 510.47 |
| Storage | -20°C |
| Solubility | DMSO (Sparingly), Methanol (Sparingly) |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial. |
