5-Amino-2-Mercaptobenzimidazole
- Product Name: 5-AMINO-2-MERCAPTOBENZIMIDAZOLE
- Product Code: ATM011IN
- CAS No: 2818-66-8
- COA: Available
- MSDS: Available
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Description
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Specification
Description
- Atom Pharma’s 5-Amino-2-mercaptobenzimidazole is a molecule recognized for its antibacterial properties. It effectively binds to the active site of bacterial ribosomes, inhibiting protein synthesis and preventing the growth of bacteria such as Staphylococcus aureus and Escherichia coli. This compound has been rigorously studied using vibrational spectroscopy, molecular modeling, and surface-enhanced Raman spectroscopy. The binding constants were determined by measuring the dissociation constant, with sodium carbonate serving as the electrolyte. The optimal concentration for this compound is maintained at an anhydrous sodium concentration of 0.1 M for maximum effectiveness.
Specification
| IUPAC NAME | 5-amino-1H-benzimidazole-2-thiol |
| CAS NO. | 2818-66-8 |
| EINECS NO. | 220 – 574 – 8 |
| FORMULA | C7H7N3S |
| MOL. WT. | 165.21 |
| InChI | 1/C7H7N3S/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,8H2,(H2,9,10,11) |
| INCHIKEY | BXDMTLVCACMNJO-UHFFFAOYAL |
| SMILES | C1CC2C(CC1N)NC([NH]2)S |
| SYNONYMS | 5-amino-1H-benzimidazole-2-thiol 5-Amino-2-Mercaptobenzimidazole; 5-Amino-2-Benzimidazolethiole; 5-Aminobenzimidazole-2-thiol; 1,3-Dihydro-5-Amino-2h-Benzimidazole-2-Thione. |
| APPLICATIONS | Intermediate for manufacture of the anti-ulcer drug Ilaprazole (PPI – Proton Pump Inhibitor). |
| “NOTE: Finished Product manufactured at our factory under the current Manufacturing process (Route of Synthesis) does not contain any secondary amines which can form Nitrosamine. The potential for presence of nitrosamine impurity is minimized. – HOD (QA) – February 5, 2020.” |
