(R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH)
Product Information:
- Product Name: (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid
- Short Name: R-CMH
- Synonyms: (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid; Pregabalin Carbamoyl Intermediate; R-CMH
- Product Code: ATM509IN
- CAS Number: 181289-33-8
- Molecular Formula: C₉H₁₇NO₃
- Molecular Weight: 187.24 g/mol
- Product Category: Chiral Pharmaceutical Intermediate / Chiral API Intermediate
- COA: Available
- MSDS/SDS: Available
-
Description
-
Specification
Description
(R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH) | CAS 181289-33-8
(R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH), also known as (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid or Pregabalin Carbamoyl Intermediate, is a high-purity chiral pharmaceutical intermediate widely used in the manufacture of CNS-active pharmaceutical ingredients, anticonvulsant drug substances, and neurology-focused therapeutic compounds. With CAS No. 181289-33-8, R-CMH serves as a critical stereochemically defined intermediate for the synthesis of high-value pharmaceutical products.
The optically active nature of R-CMH makes it particularly valuable for pharmaceutical manufacturing processes that require strict stereochemical control and high chiral purity. Due to its excellent process compatibility, controlled impurity profile, and reliable batch consistency, R-CMH is extensively used in commercial API manufacturing, pharmaceutical process development, and advanced research programs.
Atom Pharma supplies (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH) for pharmaceutical applications, with COA and MSDS available to support quality assurance and regulatory requirements.
Product Information
- Product Name: (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid
- Short Name: R-CMH
- Synonyms:
- (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid
- Pregabalin Carbamoyl Intermediate
- R-CMH
- Product Code: ATM509IN
- CAS Number: 181289-33-8
- Molecular Formula: C₉H₁₇NO₃
- Molecular Weight: 187.24 g/mol
- Product Category: Chiral Pharmaceutical Intermediate / Chiral API Intermediate
- COA: Available
- MSDS/SDS: Available
Key Features
- High-purity chiral pharmaceutical intermediate
- Suitable for regulated API manufacturing
- Excellent stereochemical consistency
- Controlled impurity profile
- High process reliability
- Consistent batch-to-batch quality
- Suitable for commercial-scale production
- Export-oriented packaging
- COA and MSDS available
Applications of (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid
- Pharmaceutical Intermediates
- Chiral API Intermediates
- CNS Drug Intermediates
- Neurology Drug Intermediates
- Anticonvulsant Drug Intermediates
- Neuropathic Pain Management Drug Intermediates
- Specialty Therapeutic Intermediates
- Pharmaceutical Process Development
- Fine Chemicals
- Research & Development Applications
Industries Served
- Pharmaceutical Manufacturing
- API Manufacturing
- Contract Development & Manufacturing Organizations (CDMOs)
- Neurology-Focused Pharmaceutical Companies
- Chiral API Manufacturers
- Specialty Chemical Industry
- Research & Development Organizations
- Pharmaceutical Process Development Companies
Packaging
- 25 Kg HDPE Drums
- Further packed with inner liner bags
Storage & Handling
Storage Conditions
- Store in airtight containers.
- Protect from direct light and moisture.
- Keep tightly closed in a cool, dry, and well-ventilated area.
- Refer to the product-specific MSDS/SDS for detailed handling and storage requirements.
Frequently Asked Questions (FAQ)
What is (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid used for?
R-CMH is primarily used as a chiral pharmaceutical intermediate in the synthesis of CNS-active, anticonvulsant, and specialty therapeutic pharmaceutical compounds.
What is the CAS number of R-CMH?
The CAS Number of (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid is 181289-33-8.
Why is R-CMH important in pharmaceutical manufacturing?
R-CMH provides a well-defined chiral structure required for pharmaceutical processes where stereochemical purity and consistency are critical.
Is COA available?
Yes, Certificate of Analysis (COA) is available upon request.
Is the product suitable for commercial-scale manufacturing?
Yes, R-CMH is suitable for commercial production, pilot-scale manufacturing, and pharmaceutical R&D applications.
Why Choose Atom Pharma?
- Reliable product quality
- Consistent batch-to-batch manufacturing
- Strong expertise in chiral intermediates
- Controlled impurity profile
- Export-focused supply capabilities
- COA and MSDS available
- Commercial-scale supply support
- Professional technical and commercial assistance
(R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid Manufacturer, Supplier & Exporter
Atom Pharma is a trusted manufacturer, supplier, and exporter of (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH), CAS 181289-33-8, for pharmaceutical and specialty chemical applications. We offer quality-assured material supported by technical documentation, export-ready packaging, and dependable commercial supply for research, pilot-scale, and industrial manufacturing requirements worldwide.
Commercial Inquiry
For product specifications, COA, MSDS, packaging requirements, pricing, and commercial inquiries related to (R)-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (R-CMH), please contact Atom Pharma’s sales team.
Specification
| TEST | SPECIFICATION |
| Description | A white powder |
| Solubility | Soluble in methanol and very slightly soluble in water |
| Identification | Should comply both tests |
| Chromatography purity | Not less than 98.0% |
| Chiral Impurity | Not more than 1.0% |
| Melting Point | Between 128℃ to 133℃ |
| Water Content | Not more than 1.0% |
| Assay by Titration | Not less than 98.0% and not more than 102% |

