Description
Cefuroxime is an enteral second-generation cephalosporin antibiotic.
As with the other cephalosporins, it is susceptible to beta-lactamase, although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike most other second-generation cephalosporins, cefuroxime can cross the blood-brain barrier.
Specification:
| Chemical Name | Cefuroxime Axetil |
| Synonyms | (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester; Altacef; Bioracef; CCI 15641; Cefaks; Cefazine; Ceftin; Cefurax; Cefuroxime 1-Acetoxyethyl Ester; Elobact; Forcef; Oraxim; Zinat; Zinnat; |
| CAS Number | 64544-07-6 |
| Molecular Formula | C₂₀H₂₂N₄O₁₀S |
| Appearance | White to Pale Yellow Solid |
| Melting Point | 108 – 120°C |
| Molecular Weight | 510.47 |
| Storage | -20°C |
| Solubility | DMSO (Sparingly), Methanol (Sparingly) |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial. |
Packaging details:
| Packaging details: | 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
| Storage: | Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
| Shelf Life: | 5 years if sealed and store away from direct sun light. |
