SAFETY DATA SHEET
SECTION 1: Identification of the substance/mixture and of the company/undertaking
- Product identifiers
Product name : 2-Chloro-N,N-dimethylpropylamine hydrochloride
Product Number : D142409
Brand : Aldrich
REACH No. : A registration number is not available for this substance as the
substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 4584-49-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Atom Pharma
280 Times Trade Centre, Puna- Simada BRTS Road, Puangam, 560100 GUJARAT, INDIA
1.4 Emergency telephone
Emergency Phone # : +91 9428888076
SECTION 2: Hazards identification
- Classification of the substance or mixture
Acute toxicity, Oral (Category 3), H301 Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Specific target organ toxicity – single exposure (Category 3), Respiratory system, H335 Short-term (acute) aquatic hazard (Category 1), H400
Long-term (chronic) aquatic hazard (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal Word Danger Hazard statement(s)
H301 Toxic if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261 Avoid breathing dust.
P264 Wash skin thoroughly after handling.
P273 Avoid release to the environment.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard Statements
none
Reduced Labeling (<= 125 ml)
Pictogram
Signal Word Danger Hazard statement(s)
H301 Toxic if swallowed.
Precautionary statement(s)
P264 Wash skin thoroughly after handling.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.
Supplemental Hazard Statements
2.3 Other hazards
none
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Ecological information:
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Toxicological information:
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
- Substances
Synonyms : 2-(Dimethylamino)isopropyl chloride β-(Dimethylamino)isopropyl chloride N-(2-Chloropropyl)dimethylamine
2-Chloro-1-(dimethylamino)propane
Formula : C5H12ClN · ClH
Molecular weight : 158,07 g/mol
CAS-No. : 4584-49-0
EC-No. : 224-971-7
| Component | Classification | Concentration |
| 2-chloropropyldimethylammonium chloride | ||
| CAS-No. 4584-49-0
EC-No. 224-971-7 |
Acute Tox. 3; Skin Irrit. 2;
Eye Irrit. 2; STOT SE 3; Aquatic Acute 1; Aquatic Chronic 1; H301, H315, H319, H335, H400, H410 |
<= 100 % |
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
- Description of first-aid measures General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 – 40 g in a 10% slurry) and consult a doctor as quickly as possible.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5: Firefighting measures
- Extinguishing media Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) Hydrogen chloride gas Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
SECTION 6: Accidental release measures
- Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
SECTION 7: Handling and storage
- Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Storage conditions
Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible
only to qualified or authorized persons. hygroscopic
Storage class
Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
- Control parameters
Ingredients with workplace control parameters
- Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating.
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:KCL 741
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:KCL 741
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type P3
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.
SECTION 9: Physical and chemical properties
- Information on basic physical and chemical properties
- Physical state crystalline
- Color beige
- Odor No data available
- Melting
point/freezing point
- Initial boiling point and boiling range
- Flammability (solid, gas)
- Upper/lower flammability or explosive limits
Melting point/range: 187 – 190 °C – lit. No data available
No data available No data available
- Flash point Not applicable
- Autoignition temperature
- Decomposition temperature
No data available No data available
- pH 5 – 6acidic, (External MSDS)
- Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available
- Water solubility soluble
- Partition coefficient: n-octanol/water No data available
- Vapor pressure No data available
- Density No data available Relative density – No data available
- Relative vapor density
- Particle – characteristics
No data available No data available
- Explosive properties No data available
- Oxidizing properties none
9.2 Other safety information
No data available
SECTION 10: Stability and reactivity
- Reactivity
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines! Violent reactions possible with:
Strong oxidizing agents
10.4 Conditions to avoid
no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5
SECTION 11: Toxicological information
- Information on toxicological effects Acute toxicity
Acute toxicity estimate Oral – 100,1 mg/kg (Expert judgment)
Inhalation: No data available Dermal: No data available
Skin corrosion/irritation Remarks: Causes skin irritation. (ECHA)
Serious eye damage/eye irritation Remarks: Causes serious eye irritation. (ECHA)
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity – single exposure
Inhalation – May cause respiratory irritation.
Specific target organ toxicity – repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information Endocrine disrupting properties Product:
Assessment The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
RTECS: TY1225000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
The following applies to aliphatic amines in general: irritations after contact with eyes and skin. Mucosal irritations, coughing, and dyspnoea after inhalation.
Under given conditions, contact with nitrites or nitric acid can lead to the formation of nitrosamines, which have shown themselves to be carcinogenic in animal experiments.
Further data:
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
SECTION 12: Ecological information
- Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Endocrine disrupting properties Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
12.7 Other adverse effects
We have no quantitative data concerning the ecological effects of this product. Further information on ecology
Discharge into the environment must be avoided.
SECTION 13: Disposal considerations
- Waste treatment methods
No data available
SECTION 14: Transport information
- UN number
ADR/RID: 2811 IMDG: 2811 IATA: 2811
14.2 UN proper shipping name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (2-chloropropyldimethylammonium chloride) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (2-chloropropyldimethylammonium chloride) IATA: Toxic solid, organic, n.o.s. (2-chloropropyldimethylammonium chloride)
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
Tunnel restriction code : (E)
Further information : No data available
SECTION 15: Regulatory information
- Safety, health and environmental regulations/legislation specific for the substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances.
H2 ACUTE TOXIC
E1 ENVIRONMENTAL HAZARDS
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
H301 Toxic if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 Toxic if swallowed.
H400 Causes skin irritation.
H410 Causes serious eye irritation.